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International Journal of Pharmacognosy and Herbal Drug Technology

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📢 Latest Update: New special issue call for papers on "Emerging Technologies in Research" - Submit by March 31, 2025

📢 Latest Update: New special issue call for papers on "Emerging Technologies in Research" - Submit by March 31, 2025

IJPHDT, Vol-2, Issue-10, Oct-2025

Volume 2, Issue 10 - undefined 2025

Volume 2 Issue 10 Cover

Issue Details:

Volume 2 Issue 10
Published:Invalid Date

Editorial: IJPHDT, Vol-2, Issue-10, Oct-2025

Welcome to the 2025 issue of International Journal of Pharmacognosy and Herbal Drug Technology. This issue showcases the remarkable breadth and depth of contemporary research across multiple disciplines. From cutting-edge applications of machine learning in climate science to the revolutionary potential of quantum computing in drug discovery, our featured articles demonstrate the power of interdisciplinary collaboration in addressing global challenges.

We are particularly excited to present research that bridges traditional academic boundaries, reflecting our journal's commitment to fostering innovation through cross-disciplinary dialogue. The integration of artificial intelligence with environmental science, the application of blockchain technology to supply chain management, and the convergence of urban planning with smart city technologies exemplify the transformative potential of collaborative research.

As we continue to navigate an era of rapid technological advancement and global challenges, the research presented in this issue offers both insights and solutions that will shape our future. We thank our authors, reviewers, and editorial board members for their continued dedication to advancing knowledge and promoting scientific excellence.

Dr. Margaret Thompson
Editor-in-Chief
International Journal of Pharmacognosy and Herbal Drug Technology

Articles in This Issue

Showing 5 of 5 articles
Research PaperID: IJPHD-00000194

Anti-Hyperlipidemic Activity of Capsicum chinense Jacq. Fruit Extract in High Fat Diet-Induced Hyperlipidemic Rats

Isha Kasar, arpan tripathi, Shahbaz Rathor

Hyperlipidemia is a major contributor to cardiovascular diseases. The present study evaluates the anti-hyperlipidemic potential of Capsicum chinense Jacq. fruit extract in high-fat diet (HFD) induced hyperlipidemic rats. Rats were divided into six groups including Normal Control, HFD Control, Standard (Atorvastatin 7.2 mg/kg), and three test groups receiving extract doses of 5, 7.5, and 10 mg/kg respectively. Significant reductions (pCapsicum chinense as a promising natural hypolipidemic agent.

Traditional UseToxicologyPharmacologyPhytochemistryCapsaicinoidsGhost Pepper+2 more
11,335 views
3,403 downloads

Contributors:

 Isha Kasar
,
 arpan tripathi
,
 Shahbaz Rathor
Research PaperID: IJPHD-00000182

Assessment of In-vivo Anti-inflammatory properties of extracts of Sida cordata

Devendra Sahu, Alok Singh Thakur

Inflammation is a complex physiological process that plays a critical role in the pathogenesis of several chronic diseases. Sida cordata (Family- Malvaceae), a medicinal plant traditionally used in Ayurvedic and ethno-medicinal systems, possesses notable anti-inflammatory potential attributed to its phytochemical constituents. The objective is to assess the in-vivo anti-inflammatory activity of water and acetic acid extract of Sida cordata using the carrageenan-induced paw edema model in rats. Albino rates were divided into four groups (n=6 each): Control, carrageenan control, Water extract (100 & 200 mg/kg), and Acetic acid extract (100 & 200 mg/kg). Inflammation was induced by injecting 0.1 mL of 1% carrageenan into the subplanter region of the left hind paw. Paw volume was measured at 0, 1, 2, 3, 4 and 24 hours post-injection using a Varner caliper. The percentage inhibition of paw edema was calculated, and data were analyzed using one-way ANOVA followed by post Tukey’s test. Both extracts significantly reduce power edema volume compared to the control. The water extract showed a greater reduction in inflammation throughout the observation. Maximum inhibition was observed at the 4th hour post carrageenan injection. Water and acetic acid extracts of Sida cordata demonstrate significant in vivo anti-inflammatory activity supporting its traditional use in inflammatory disorders. Further isolation of the bioactive compound and mechanistic studies are warranted.

Artificial IntelligenceClinical Pharmacist Pharmacy AutomationPharmacovigilanceEthical AI
10,778 views
3,334 downloads

Contributors:

 Devendra Sahu
,
 Alok Singh Thakur
Research PaperID: IJPHD-00000193

Bhut Jholokia Demystified: Insights into the World’s Hottest Chili

Isha Kasar, Arpan Kumar Tripathi, Shahbaz Rathor

Bhut Jholokia, or "Bhut Jolokia" or "ghost pepper" (Capsicum chinense Jacq.), is one of the world's hottest chili varieties and an important part of the ethnobotany of northeast India. Its high capsaicinoid content has created a lot of interest in its phytochemical chemistry and wide range of biological activities, such as analgesic and anti-inflammatory activities, antimicrobial and anticancer activities, metabolic modulation, and possible cardiovascular benefits. This review offers a concise synthesis of its botanical characterization, traditional therapy, phytochemical profile, pharmacology, toxicology, and agronomic and quality concerns. It also highlights current knowledge gaps and suggests research priorities for upcoming translational and clinical investigations.

Energy MetabolismInflammationFecal Microbiota TransplantationShort-Chain Fatty AcidsDysbiosisDiabetes+2 more
10,917 views
3,296 downloads

Contributors:

 Isha Kasar
,
 Arpan Kumar Tripathi
,
 Shahbaz Rathor
Research PaperID: IJPHD-00000186

Formulation and Evaluation of a Standardized Polyherbal Syrup with Optimized Pharmacological Activities

Soumya Kanta Mishra, Somanath Padhan

The current investigation is dedicated to the development and assessment of a standardised polyherbal syrup that has optimal pharmacological properties and incorporates the principles of pharmacognostic and current methods of analysis to guarantee effectiveness, safety and stability. The syrup was formulated based on aqueous extraction, hydro alcoholic extraction, physicochemical standardization and chromatographic fingerprinting (HPTLC, HPLC, FTIR). The syrup was composed of standardized extracts including Curcuma longa, Withania somnifera, Phyllanthus emblica, and Tinospora cordifolia. The preclinical animal research showed: large antioxidant, hepatoprotective, anti-inflammatory, and antidiabetic effects: the synergistic interaction between herbs and the optimization of pharmacodynamics. Toxicological analyses showed that it was safe with no adverse biochemical or histopathological changes at a dose of up to 2000 mg/kg. The formulation was highly stable with accelerated conditions and had a high level of phytochemical integrity. The implications of these findings are that, standardized polyherbal syrups can be a safe, effective, and reproducible therapeutic substitute to synthetic drugs, and future pharmacokinetic, mechanistic, and clinical studies are warranted.

Animal Models.ChitosanFenugreek GumTamarind GumXanthan GumNatural Polymers+2 more
11,078 views
3,246 downloads

Contributors:

 Soumya Kanta Mishra
,
 Somanath Padhan
Research PaperID: IJPHD-00000183

Pharmacognostic Standardization and Quality Controlled Parameters of Polyherbal Formulations

S. Shruti Shruti, Pooja Sharma, Pradeep Dhaked, Rishu Sharma, Aarohi Parmar

This is a synthesis review of animal evidence on the pharmacognostic standardization and quality-controlled parameters of polyherbal preparations extending to macroscopic and microscopic validation, physicochemical and phytochemical profiling, chromatographic fingerprinting (HPTLC/HPLC), and in vivo pharmacological validation in rodents. Revolving around preclinical research, the review records that morphologically identical, ash and extractive value and chemical fingerprint standardized formulations are more consistent in and reproducible therapeutic effects, mostly which are anti-inflammatory, hepatoprotective, antioxidant, and antidiabetic, in Wistar, Sprague Dawley and Swiss albino. Associations of the integrity of chromatographic markers with normalization of biochemical indices (ALT, AST, ALP, SOD, CAT, GPx and fasting glucose) highlight the practical relevance of analytical-biological analysis. Nonetheless, there are still unresolved inconsistencies such as inter-laboratory inconsistency, lack of harmonized world standards regarding multi-herbal products, lack of application of sophisticated analytics (LC-MS, NMR, metabolomics), and insufficient research on herb-herb pharmacokinetics/pharmacodynamics. Standardized pharmacognostic-analytical protocols, integration of contemporary chemometric and omics approaches, development of validated digital reference libraries and greater long-term and mechanism-based animal studies should therefore be adopted to enhance quality assurance and translational potential of polyherbal therapeutics.

Water ExtractAnti-InflammatoryInflammation ManagementCarrageenan- Induced Paw EdemaSida Cordata
11,059 views
3,348 downloads

Contributors:

 S. Shruti Shruti
,
 Pooja Sharma
,
 Pradeep Dhaked
,
 Rishu Sharma
,
 Aarohi Parmar

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