Neuroprotection

Traditional Chinese Medicine (TCM) plants have been known to confer beneficial therapeutic effects in the traditional systemic Chinese Medicinal, but a science-based verification is important to offer evidence-based utilization. This review will cover or discuss the pharmacological prospect of TCM plants, including Andrographis paniculata, Glycyrrhiza glabra, Scutellaria baicalensis, astragalus membranaceus, ginkgo biloba and panax ginseng using the preclinical study in animals. These investigations indicate a high level of antiviral, anti-inflammatory, immuno-modulator, anti-oxidant, heendoguinative proteomin and neuro-protection, which have been explained through recent pharmacognostic strategies such as phytochemical screening, chromatographic studies, in-vitro tests, as well as molecular analyses. Although translation into humans is impeded by species-specific effects, complex, formulations and reproducibility, the incorporation of standardized extracts, high- fidelity disease models, and increasing ethical options all improve the translational significance. The results indicate the possible potential in TCM plants as evidence-based human and veterinary medicines and point to possible areas of future intensive preclinical and clinical studies.

Background: Prolonged exposure to ultraviolet (UV) radiation may result in sunburn, accelerated aging, cutaneous damage, and potentially, carcinoma of the skin. While effective, synthetic sunscreens are frequently linked to dermal irritation and possible toxicity. Herbal sunscreens, formulated with natural, plant-derived compounds, present a more secure and ecologically sound alternative. Objective: To develop and evaluate a herbal sunscreen lotion utilizing plant extracts possessing established UV-protective, antioxidant, and skin-soothing properties. Materials and Methods: Herbal extracts derived from Aloe vera, Watermelon, Sandalwood, and Turmeric were selected based on their photoprotective and antioxidant capabilities. The lotion base was prepared utilizing conventional emulsification methodologies. Physicochemical properties, including pH, viscosity, spreadability, and stability, in-vitro sun protection factor determined via UV spectrophotometry were evaluated for the formulated herbal sunscreen lotion. Results: The herbal sunscreen lotion exhibited acceptable spreadability, stability under diverse storage conditions, and an appropriate pH (5.5–6.5). Confirmation of effective UV-B protection was established by the moderate range (SPF 15–25) of the in-vitro SPF value. The presence of significant antioxidant activity suggested the potential for skin protection from oxidative damage. Conclusion: The herbal sunscreen cream exhibits potential antioxidant properties in conjunction with ultraviolet (UV) protection. It serves as a safe, natural, and efficient alternative to chemical sunscreens, demonstrating commercialization potential.