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International Journal of Pharmacognosy and Herbal Drug Technology

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📢 Latest Update: New special issue call for papers on "Emerging Technologies in Research" - Submit by March 31, 2025

📢 Latest Update: New special issue call for papers on "Emerging Technologies in Research" - Submit by March 31, 2025

IJPHDT, Vol-1, Issue-1, Dec-2025

Volume 1, Issue 1 - undefined 2025

Volume 1 Issue 1 Cover

Issue Details:

Volume 1 Issue 1
Published:Invalid Date

Editorial: IJPHDT, Vol-1, Issue-1, Dec-2025

Welcome to the 2025 issue of International Journal of Pharmacognosy and Herbal Drug Technology. This issue showcases the remarkable breadth and depth of contemporary research across multiple disciplines. From cutting-edge applications of machine learning in climate science to the revolutionary potential of quantum computing in drug discovery, our featured articles demonstrate the power of interdisciplinary collaboration in addressing global challenges.

We are particularly excited to present research that bridges traditional academic boundaries, reflecting our journal's commitment to fostering innovation through cross-disciplinary dialogue. The integration of artificial intelligence with environmental science, the application of blockchain technology to supply chain management, and the convergence of urban planning with smart city technologies exemplify the transformative potential of collaborative research.

As we continue to navigate an era of rapid technological advancement and global challenges, the research presented in this issue offers both insights and solutions that will shape our future. We thank our authors, reviewers, and editorial board members for their continued dedication to advancing knowledge and promoting scientific excellence.

Dr. Margaret Thompson
Editor-in-Chief
International Journal of Pharmacognosy and Herbal Drug Technology

Articles in This Issue

Showing 6 of 6 articles
Research PaperID: IJPHD-00000010

Antimicrobial, Anti-Inflammatory and Wound Healing Activity of Polyherbal Formulation

Chandra Prakash Dwivedi, Govind Sharma, D. K. Pradhan

The antibacterial, anti-inflammatory, and wound-recovery houses of a polyherbal methanolic extract (PHME) made from Argemone mexicana, Datura stramonium, and Plumbago zeylanica are tested in this study. Staphylococcus aureus, Bacillus subtilis, Escherichia coli, and Pseudomonas aeruginosa had been the 4 bacterial traces towards which the antibacterial pastime of PHME became assessed in vitro the use of techniques such as broth dilution and agar well diffusion. In assessment to the diverse plant extracts, the consequences indicated that PHME had the bottom minimal inhibitory concentrations (MICs) and the widest zones of inhibition, indicating its higher antibacterial effectiveness. According to the examine, PHME's antibacterial performance became on par with that of the commonplace antibiotic, Ofloxacin, particularly whilst it came to Staphylococcus aureus. The antibacterial pastime of PHME become drastically extra than that of the separate extracts, in line with statistical analysis. These consequences mean that PHME has wonderful healing promise alternatively for traditional antibiotics, with potential makes use of in wound healing and the treatment of bacterial infections. To completely inspect its healing variety and medical utility, greater research is needed.

Pseudomonas AeruginosaEscherichia ColiStaphylococcus AureusAgar Well DiffusionMinimum Inhibitory Concentration (MIC)Anti-Inflammatory+2 more
1,203 views
504 downloads

Contributors:

 Chandra Prakash Dwivedi
,
 Govind Sharma
,
 D. K. Pradhan
Research PaperID: IJPHD-00000014

Assessing the Root of Mimosa Pudica for Wound Healing

Jay Chandra, Dhanesh Sahu

The primary goal of this investigation is to apply rational methods to handle the differentiation of the active components and pharmacological properties of the shoot and root extracts of Mimosa pudica Linn. The methanolic extracts of the shoots and roots of Mimosa pudica demonstrated exceptional wound healing efficacy when compared to the widely used medication Gentamicin. However, the Mimosa pudica root Chloroform Extract yielded some unsettling results (MRCE). We used UV and IR spectroscopy to illustrate the isolated mixes. In an ongoing report, the genuine potential of this ethanolic extract of Mimosa pudica Linn. leaves as a wound treatment was examined. The plant belongs to the Mimisace family as an individual. An ethanol extract of Mimosa pudica leaves was tested for its ability to heal wounds in rodents using consumption and extraction wound models. Compared to the benchmark group's 28% wound region, the extract-treated animals displayed a 73% decrease in wound region with the 5%w/w detailing and a 92% decline with the 10%w/w definition. In comparison to the control wounds, the extract-treated wounds in the extraction model exhibited quicker epithelialization and narrowing. This was confirmed by the results of the histological review. Researchers discovered that the greater the use of natural extracts, the more often wound constrictions occurred. The highest quality level found in the two assortments is mupirocin. Mimosa pudica has a remarkable effect on diabetic rodents' wound healing; further research on this benefit in humans is advised.

MRMMSMEwound healing activityMimosa pudica
2,100 views
503 downloads

Contributors:

 Jay Chandra
,
 Dhanesh Sahu
Research PaperID: IJPHD-00000013

Central Nervous System Activity of Acute Administration of Ethanol Extract of Punica Granatum L. Seeds in Mice

Akansha Bhadarkar, Vikas Sahu

This study examines the effects of acutely administering an ethanol extract of Punica granatum L.seeds on the activity of the central nervous system (CNS) in mice. The open field test (OFT),elevated plus maze (EPM), and rotarod test were among the behavioural tests used to assessthe effects of the ethanol extract, which was made from dried and powdered pomegranate seeds.These assessments evaluated motor coordination, anxiety-like behaviour, and locomotoractivity. The findings showed that the ethanol extract had a considerable impact on centralnervous system activity, as evidenced by dose-dependent alterations in anxiety-relatedbehaviours and motor function. The extract showed possible CNS-stimulating and anxiolyticeffects, confirming Punica granatum seeds' potential as a treatment for anxiety and motordysfunction. These results lay the groundwork for additional investigation into the bioactivesubstances causing the effects seen and their possible therapeutic uses in diseases relating tothe central nervous system.

Central Nervous System (CNS) (Acute Administration of Ethanol Extract Punic
1,784 views
557 downloads

Contributors:

 Akansha Bhadarkar
,
 Vikas Sahu
Research PaperID: IJPHD-00000012

Evaluation of Anti-Ulcer Activity of The Leaf Extract of Osyris Quadripartita Decne. (Santalaceae) In Rats

Pritam Bhore, Arpan Tripathi

This study investigates the anti-ulcer potential of Osyris quadripartita leaf extract using albino Wistar rats as an experimental model. The extract was prepared by Soxhlet extraction with methanol and its efficacy was evaluated in both ethanol and indomethacin-induced ulcer models, which simulate different ulcerogenesis mechanisms. Rats were treated with varying doses of the extract (100, 200, and 400 mg/kg) for 7 days, alongside a standard group receiving omeprazole. The outcomes were assessed through gastric juice pH measurement, ulcer index scoring, and histological examination of gastric tissue. Results showed a dose-dependent reduction in ulcer severity and an increase in gastric pH, suggesting enhanced mucosal protection. The 400 mg/kg dose demonstrated comparable effectiveness to omeprazole. The study provides scientific evidence supporting the gastroprotective properties of Osyris quadripartita, highlighting its potential as a natural remedy for peptic ulcer.

ulcergastric juice pHomeprazolealbino Wistar ratsindomethacin-induced ulcersethanol-induced ulcers+3 more
1,768 views
457 downloads

Contributors:

 Pritam Bhore
,
 Arpan Tripathi
Research PaperID: IJPHD-00000011

In Vitro Anticancer Activity of Eclipta Alba Whole Plant Extract on Colon Cancer

Pratibha Sahu, Swapnil Deshmukh

The study reports the anticancer activity of the methanolic extract of Eclipta alba on two human colon cancer cell lines, namely HCT-116 and HT-29. In simple terms, the objectives of the research include the cytotoxic efficacy of the extract, its capability to inhibit cellular migration, and its importance in colony formation. The extract showed significant cytotoxic effects on its subordinates with IC₅₀ values ranging between 200 to 400 μg/mL in an array of assays used, such as MTT, wound healing, and clonogenic assays. There is impressive selectivity toxicity since it can spare the normal fibroblast cells-WI-38. This is a proof that it can be especially defined as an anticancer drug. Furthermore, the results have established that the extract has the ability to inhibit cancer cell migration and colony formation; therefore, it can functionally represent such a potential for the very crucial cancer treatment and prevention of metastasis. These observations are consistent with the previous study, and this fosters the vision that Eclipta alba is a potentially useful drug from nature as a natural medicinal drug. For further studies, its application should be developed for cancer therapy with research based on its bioactive combinations, subatomic components, and in vivo adequacy.

cytotoxicityHT-29HCT-116colon cancermethanolic extractAnticancer activity
1,468 views
470 downloads

Contributors:

 Pratibha Sahu
,
 Swapnil Deshmukh
Research PaperID: IJPHD-00000015

Synthesis of Silver Nanoparticles from Plant Extracts and Their Potential Applications in Cancer Treatment: A Comprehensive Review

Apurva Yadav, Deleshwar Sahu

This comprehensive assessment explores the synthesis of silver nanoparticles (AgNPs) from plant extracts and their capacity applications in most cancers treatment. AgNPs, synthesized thru eco-friendly techniques the usage of plant assets, have garnered extensive interest because of their biocompatibility, ease of synthesis, and effective anticancer houses. The assessment discusses numerous plant assets used for the inexperienced synthesis of AgNPs, highlighting their role in stabilizing and functionalizing the nanoparticles. The anticancer mechanisms of AgNPs, including oxidative stress induction, DNA harm, and modulation of cellular signaling pathways, are examined, along with their capacity in treating various types of cancers. The overview additionally addresses essential troubles related to the toxicity and biocompatibility of AgNPs, emphasizing the want for cautious evaluation before clinical utility. Furthermore, the paper identifies key demanding situations in cancer treatment and descriptions destiny studies directions to decorate the efficacy of AgNPs, together with the improvement of targeted drug transport structures and their aggregate with different therapeutic modalities. The evaluation underscores the significant potential of AgNP-based cures in revolutionizing cancer treatment, at the same time as also highlighting the gaps in present day expertise and the want for similarly research to ensure their secure and powerful use.

Drug delivery systemsOxidative stressAnticancer propertiesGreen synthesisPlant extractsSilver nanoparticles (AgNPs)
1,936 views
720 downloads

Contributors:

 Apurva Yadav
,
 Deleshwar Sahu

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