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International Journal of Pharmacognosy and Herbal Drug Technology

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📢 Latest Update: New special issue call for papers on "Emerging Technologies in Research" - Submit by March 31, 2025

📢 Latest Update: New special issue call for papers on "Emerging Technologies in Research" - Submit by March 31, 2025

IJPHDT, Vol-1, Issue-6, Jan-2025

Volume 1, Issue 6 - undefined 2025

Volume 1 Issue 6 Cover

Issue Details:

Volume 1 Issue 6
Published:Invalid Date

Editorial: IJPHDT, Vol-1, Issue-6, Jan-2025

Welcome to the 2025 issue of International Journal of Pharmacognosy and Herbal Drug Technology. This issue showcases the remarkable breadth and depth of contemporary research across multiple disciplines. From cutting-edge applications of machine learning in climate science to the revolutionary potential of quantum computing in drug discovery, our featured articles demonstrate the power of interdisciplinary collaboration in addressing global challenges.

We are particularly excited to present research that bridges traditional academic boundaries, reflecting our journal's commitment to fostering innovation through cross-disciplinary dialogue. The integration of artificial intelligence with environmental science, the application of blockchain technology to supply chain management, and the convergence of urban planning with smart city technologies exemplify the transformative potential of collaborative research.

As we continue to navigate an era of rapid technological advancement and global challenges, the research presented in this issue offers both insights and solutions that will shape our future. We thank our authors, reviewers, and editorial board members for their continued dedication to advancing knowledge and promoting scientific excellence.

Dr. Margaret Thompson
Editor-in-Chief
International Journal of Pharmacognosy and Herbal Drug Technology

Articles in This Issue

Showing 6 of 6 articles
Research PaperID: IJPHD-00000023

A Comprehensive Analysis of Herbal Medicine's Possible Use in The Management of Chronic Kidney Disease

Anil Kumar, Govind Sharma, D. K. Pradhan

This is a systematic review on herbal medicine's potential role in managing CKD, a progressive condition that poses much health concern worldwide. It explores medicinal plants, including Phyllanthus niruri, Salvia miltiorrhiza, and Withania somnifera, that exhibit nephroprotective properties, such as antioxidant, anti-inflammatory, and anti-fibrotic properties. These therapies have been designed to target the mechanisms of their action through the modulation and reduction of fibrosis with a resultant increase in kidney function and slowing of the progression of CKD. While such encouraging preclinical and clinical data are available, clinical application challenges include standardisation, herb-drug interaction, and regulatory restrictions. The review strongly focuses on this combination of these natural remedies to benefit synergistically with conventional treatments, reduce cost in treatment delivery, and have sustainable solutions for delivering healthcare. Since this analysis now creates a path toward standard protocols and potential further research, more holistic CKD care is approached.

GlycemicDiabetes TreatmentInsulin DeliveryGlucose-responsive microneedleBiodegradable
2,082 views
730 downloads

Contributors:

 Anil Kumar
,
 Govind Sharma
,
 D. K. Pradhan
Research PaperID: IJPHD-00000024

An Evaluation of The Effectiveness and Safety of Herbal Remedies for Stomach Ulcers

Durgesh Kumar, Kedarnath Yadav

The study presented here was designed to establish the efficacy and safety of herbal remedy treatments for stomach ulcers when compared to conventional medication. A mixed-methods research design using a randomized controlled trial was combined with qualitative interviews of patients. The sample was composed of 200 participants with a diagnosis of mild to moderate stomach ulcers, randomly assigned to either an experimental or control group. The herbal remedy group received a combination of Glycyrrhiza glabra, Aloe vera, Zingiber officinale, and Curcuma longa, while controls received standard PPIs or H2 receptor antagonists, along with antibiotics if H. pylori was present. Data were collected at baseline, 4 weeks, and 8 weeks, assessing ulcer healing rates, symptom relief, and side effects. No significant differences in ulcer healing rates were found between the two groups: 88% versus 82% after 8 weeks, p = 0.299. In both groups, there was a significant alleviation of symptoms: reduction of pain, bloating, and nausea; p = 0.001, 0.005, and 0.002, respectively. Side effects were similar in both groups, with gastrointestinal discomfort being the most frequent but not significantly different between the groups, p = 0.365. Qualitative data, through interviews among the patients, showed that 60% of the patients preferred herbal remedies because of lesser side effects and a more natural approach to the treatment of their ailment. This study is, therefore, conclusive that herbal remedies are equally effective and safe as conventional treatments in managing stomach ulcers, although most patients have expressed preference for the former.

End-Stage Renal DisorderChronic Kidney DiseaseManagementHerbal Medicine
2,060 views
721 downloads

Contributors:

 Durgesh Kumar
,
 Kedarnath Yadav
Research PaperID: IJPHD-00000026

An Evidence-Based Overview of The Use of Nutritional Supplements and Herbal Remedies for Ocular Diseases

Hemkanti Patel, Durgesh Kumar

Ocular diseases, such as age-related macular degeneration (AMD), cataracts, glaucoma, and diabetic retinopathy, contribute significantly to the global burden of visual impairment and blindness and pose significant health and economic challenges. This review discusses using nutritional supplements and herbal remedies as adjuncts to ocular health. Key findings show that carotenoids lutein and zeaxanthin could retard the progression of age-related macular degeneration, omega-3 fatty acids, dry eye syndrome and diabetic retinopathy as such, have been cured by having vitamins A, C, and E, which basically help decrease oxidative stress. Herbal-based treatments like Ginkgo biloba, Bilberry (Vaccinium myrtillus), and Curcuma longa are promising due to their antioxidant, anti-inflammatory, and vascular-enhancing qualities. Whereas such improvement might prevail, others, like variation in preparations, imbalanced dosing, and the need for rigorous randomized control trials, remain. The present review underlines the necessity of incorporating these natural interventions into evidence-based ophthalmic care while rectifying the standardization and regulatory gaps for safe and effective treatment. Establishing these interventions as viable, accessible, and sustainable solutions for preserving vision and contributing to a better quality of life worldwide will require further research.

Oxidative stress ReductionDopaminergic neuronDopamine levelsParkinson’s DiseaseHerbal Remedy
2,451 views
689 downloads

Contributors:

 Hemkanti Patel
,
 Durgesh Kumar
Research PaperID: IJPHD-00000028

Antioxidant and Hepatoprotective Properties of Standardised Herbal Extracts

Ansul Ram, Deleshwar Kumar

being a major contributor to liver damage. The present review has focused attention on the antioxidant and hepatoprotective properties of standardised herbal extracts, which can represent a natural and sustainable solution for liver health. Standardisation makes it possible to ensure consistency in the concentration of bioactive compounds, enhancing the reliability and efficacy of these herbal remedies. Key extracts, such as silymarin from Silybum marianum, curcumin from Curcuma longa, and lignans from Phyllanthus amarus, exhibit strong antioxidant properties by scavenging free radicals, preventing lipid peroxidation and regulating inflammatory pathways. Their clinical and preclinical evidence has proved them to be effective in treating liver diseases such as non-alcoholic fatty liver disease, drug-induced liver injury, and viral hepatitis. Despite their promises, some hurdles still face them, including variability in raw materials, low bioavailability, and regulatory gaps. This review calls for further optimization of bioavailability as well as the synergistic effects of phytochemicals along with the availability of global regulatory standards to establish standardized herbal extracts as effective integrative therapeutic options for liver health.

Liver disease management.Herbal medicineHepatoprotective effectsLiver disorders
2,571 views
757 downloads

Contributors:

 Ansul Ram
,
 Deleshwar Kumar
Research PaperID: IJPHD-00000025

Protective Effect of a New Herbal Remedy on A Parkinson's Disease Model in Rats

Deleshwar Kumar, Kedarnath Yadav

This study investigates the neuroprotective effects of a new herbal extract using a rat model of Parkinson's disease. A total of 100 male Wistar rats were employed in this study, dividing the animals into five groups: one for control, one for PD, and three for low, moderate, and high dosages of the herbal remedy. Behavioural tests of rotarod and open field, biochemical analysis for dopamine levels and markers of oxidative stress, and histological assessments for surviving dopaminergic neurons were done for four successive weeks. Improvements in motor coordination, reductions in oxidative stress, increase in dopamine levels, and survival of dopaminergic neurons showed significant improvements within herbal remedy-treated groups, with high doses showing the most pronounced effect.

Randomized Controlled Trial (RCT)SafetyEffectivenessStomach UlcersHerbal Remedies
2,377 views
706 downloads

Contributors:

 Deleshwar Kumar
,
 Kedarnath Yadav
Research PaperID: IJPHD-00000027

Treatment of Liver Problems Using Herbal Medicine

Neha Mandle, Deleshwar Sahu

The disorders that affect the liver are a significant contributor to the morbidity and mortality rates that are experienced all over the world. Due to its natural bioactive chemicals, its cost-effectiveness, and the fact that it has fewer adverse effects, herbal medicine has gained popularity as a complementary and alternative strategy. It discussed the details regarding the important medicinal herbs including the hepatoprotective effects of milk thistle, turmeric, and liquorice, the mechanism of actions and clinical efficacies in relation to a potential application within strategies to address liver disease management. Despite the promising, there is also a lot pointed out by its problems that it has-standardisation, interactions of herbs with drugs and limited large scale trials. This way forwards to more avenues of further research.

Age-Related Eye Disease Study (AREDS).Age-Related Macular Degeneration (AMD)Ocular DiseasesHerbal RemediesNutritional Supplements
2,805 views
770 downloads

Contributors:

 Neha Mandle
,
 Deleshwar Sahu

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