Antioxidant and Hepatoprotective Properties of Standardised Herbal Extracts
Published in IJPHDT, Vol-1, Issue-6, Jan-2025 (Vol. 1, Issue 6, 2025)
Abstract
Authors (2)
Ansul Ram
View all publications →Deleshwar Kumar
KIPS, Shrishankaracharya Professional University, (C.G). India
View all publications →Download Article
Best for printing and citation
Best for printing and citation
Article Information
- Article ID:
- IJPHD-00000028
- Paper ID:
- IJPHD-01-000028
How to Cite
Ram & , D. (2025). Antioxidant and Hepatoprotective Properties of Standardised Herbal Extracts. International Journal of Pharmacognosy and Herbal Drug Technology, 1(6), xx-xx. https://ijphdt.scholarjms.com/articles/12
Article Actions
Article Impact
More from this Issue
A Comprehensive Analysis of Herbal Medicine's Possible Use in The Management of Chronic Kidney Disease
This is a systematic review on herbal medicine's potential role in managing CKD, a progressive condition that poses much health concern worldwide. It explores medicinal plants, including Phyllanthus niruri, Salvia miltiorrhiza, and Withania somnifera, that exhibit nephroprotective properties, such as antioxidant, anti-inflammatory, and anti-fibrotic properties. These therapies have been designed to target the mechanisms of their action through the modulation and reduction of fibrosis with a resultant increase in kidney function and slowing of the progression of CKD. While such encouraging preclinical and clinical data are available, clinical application challenges include standardisation, herb-drug interaction, and regulatory restrictions. The review strongly focuses on this combination of these natural remedies to benefit synergistically with conventional treatments, reduce cost in treatment delivery, and have sustainable solutions for delivering healthcare. Since this analysis now creates a path toward standard protocols and potential further research, more holistic CKD care is approached.
An Evaluation of The Effectiveness and Safety of Herbal Remedies for Stomach Ulcers
The study presented here was designed to establish the efficacy and safety of herbal remedy treatments for stomach ulcers when compared to conventional medication. A mixed-methods research design using a randomized controlled trial was combined with qualitative interviews of patients. The sample was composed of 200 participants with a diagnosis of mild to moderate stomach ulcers, randomly assigned to either an experimental or control group. The herbal remedy group received a combination of Glycyrrhiza glabra, Aloe vera, Zingiber officinale, and Curcuma longa, while controls received standard PPIs or H2 receptor antagonists, along with antibiotics if H. pylori was present. Data were collected at baseline, 4 weeks, and 8 weeks, assessing ulcer healing rates, symptom relief, and side effects. No significant differences in ulcer healing rates were found between the two groups: 88% versus 82% after 8 weeks, p = 0.299. In both groups, there was a significant alleviation of symptoms: reduction of pain, bloating, and nausea; p = 0.001, 0.005, and 0.002, respectively. Side effects were similar in both groups, with gastrointestinal discomfort being the most frequent but not significantly different between the groups, p = 0.365. Qualitative data, through interviews among the patients, showed that 60% of the patients preferred herbal remedies because of lesser side effects and a more natural approach to the treatment of their ailment. This study is, therefore, conclusive that herbal remedies are equally effective and safe as conventional treatments in managing stomach ulcers, although most patients have expressed preference for the former.
Protective Effect of a New Herbal Remedy on A Parkinson's Disease Model in Rats
This study investigates the neuroprotective effects of a new herbal extract using a rat model of Parkinson's disease. A total of 100 male Wistar rats were employed in this study, dividing the animals into five groups: one for control, one for PD, and three for low, moderate, and high dosages of the herbal remedy. Behavioural tests of rotarod and open field, biochemical analysis for dopamine levels and markers of oxidative stress, and histological assessments for surviving dopaminergic neurons were done for four successive weeks. Improvements in motor coordination, reductions in oxidative stress, increase in dopamine levels, and survival of dopaminergic neurons showed significant improvements within herbal remedy-treated groups, with high doses showing the most pronounced effect.