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International Journal of Pharmacognosy and Herbal Drug Technology

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Pharmacognosy of Marine-Derived Natural Products: A Frontier in Anti-Cancer Research

Published in IJPHDT, Vol-2, Issue-8, Aug-2025 (Vol. 2, Issue 8, 2025)

Pharmacognosy of Marine-Derived Natural Products: A Frontier in Anti-Cancer Research - Issue cover

Abstract

Natural products of marine origin have become an attractive area in the search of new anti-cancer agents because of their distinct chemical novelty and the presence of strong bioactive substances. This study was intended to examine pharmacognostic potential of a few marine-derived compounds on cancer cell proliferation in animal experimental models. Marine sponges and algae were extracted crudely and screened phytochemically, and then in vivo assayed in tumor-induced mice models. The information was obtained by the measurement of tumor volume, analysis of survival rates, and histopathological tests. It was found that alkaloids isolated in marine sponges showed a significant decrease of the tumor volume (mean = 45.2 mm 3, SD = 4.8) compared to control (mean = 92.6 mm 3, SD = 6.2), whereas terpenoids isolated in algae increased survival rates and caused strong apoptosis in cancerous tissues. In general, the results indicate that bioactive compounds of marine origin have strong anti-cancer activity, which underlines their significance as new pharmacognostic sources of cancer treatment. The paper highlights the need of marine pharmacognosy in the broadening of natural product-based drug discovery and suggests additional research to achieve efficacy, safety, and mechanistic insights.

Authors (2)

Divyani Thakur

Chhatrapati Shivaji institute of Pharmacy, Kolihapuri, Balod road, Pulgao, Durg Pin – 490001, India

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Gaurav Kumar Sahu

Chhatrapati Shivaji institute of Pharmacy, Kolihapuri, Balod road, Pulgao, Durg

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Article Information

Article ID:
IJPHD-00000131
Paper ID:
IJPHD-01-000131

How to Cite

, D. & Gaurav Kumar Sahu (2025). Pharmacognosy of Marine-Derived Natural Products: A Frontier in Anti-Cancer Research. International Journal of Pharmacognosy and Herbal Drug Technology, 2(8), xx-xx. https://ijphdt.scholarjms.com/articles/62

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