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International Journal of Pharmacognosy and Herbal Drug Technology

📢 Latest Update: New special issue call for papers on "Emerging Technologies in Research" - Submit by March 31, 2025

📢 Latest Update: New special issue call for papers on "Emerging Technologies in Research" - Submit by March 31, 2025

IJPHDT, Vol-2, Issue-3, March-2025

Volume 2, Issue 3 - undefined 2025

Volume 2 Issue 3 Cover

Issue Details:

Volume 2 Issue 3
Published:Invalid Date

Editorial: IJPHDT, Vol-2, Issue-3, March-2025

Welcome to the 2025 issue of International Journal of Pharmacognosy and Herbal Drug Technology. This issue showcases the remarkable breadth and depth of contemporary research across multiple disciplines. From cutting-edge applications of machine learning in climate science to the revolutionary potential of quantum computing in drug discovery, our featured articles demonstrate the power of interdisciplinary collaboration in addressing global challenges.

We are particularly excited to present research that bridges traditional academic boundaries, reflecting our journal's commitment to fostering innovation through cross-disciplinary dialogue. The integration of artificial intelligence with environmental science, the application of blockchain technology to supply chain management, and the convergence of urban planning with smart city technologies exemplify the transformative potential of collaborative research.

As we continue to navigate an era of rapid technological advancement and global challenges, the research presented in this issue offers both insights and solutions that will shape our future. We thank our authors, reviewers, and editorial board members for their continued dedication to advancing knowledge and promoting scientific excellence.

Dr. Margaret Thompson
Editor-in-Chief
International Journal of Pharmacognosy and Herbal Drug Technology

Articles in This Issue

Showing 6 of 6 articles
Research PaperID: IJPHD-00000043

Comparative Study of Extraction Methods for Enhancing the Yield of Medicinal Plant Alkaloids

Hemkanti Patel, Neha Mandle

This research is a comparative study of various extraction techniques to improve alkaloid yield and purity from medicinal plants. Alkaloids, with their broad spectrum of pharmacological activities including anticancer, analgesic, and antimalarial activities, are key bioactive molecules in pharmaceutical uses. The research assesses both traditional extraction methods—maceration and Soxhlet—and innovative techniques—Microwave-Assisted Extraction (MAE), Ultrasound-Assisted Extraction (UAE), Accelerated Solvent Extraction (ASE), and Solid Phase Extraction (SPE). Three medicinal plants rich in alkaloids (Rauwolfia serpentina, Catharanthus roseus, and Papaver somniferum) were chosen for the investigation. The techniques were evaluated on the basis of yield percentage, extraction time, solvent usage, and purity of extracts (evaluated through HPLC). Findings indicated that ASE and MAE performed significantly better than conventional techniques, providing higher purity and yield with less time and solvent consumption. SPE, employed as a purification process, also enhanced the quality of extracts. The findings support eco-friendly, new extraction methods in pharmaceutical and biotechnology, offering effective alternatives to existing approaches. The research standardizes alkaloid extraction methods for natural product research and industry.

3,401 views
1,094 downloads

Contributors:

 Hemkanti Patel
,
 Neha Mandle
Research PaperID: IJPHD-00000044

Ethnobotanical Survey and Pharmacognostic Profiling of Medicinal Plants Used in Wound Healing

Arnav Roy, Govind Sharma

This research, "Ethnobotanical Survey and Pharmacognostic Profiling of Medicinal Plants Used in Wound Healing," sets out to record the traditional medicinal plants utilized to heal wounds and scientifically assess their pharmacognostic attributes. Carried out in a chosen rural area in India, the research utilizes an ethnobotanical survey using formal interviews with traditional practitioners and local healers to determine popular plant species in use. 25 medicinal plants were screened and examined with macroscopic, microscopic, physicochemical, and phytochemical screening for their bioactive potential. Results show that the most common phytochemicals are flavonoids (92%) and tannins (88%), responsible for tissue regeneration and antimicrobial activity. Their anti-inflammatory and antiseptic activities are brought about by alkaloids (76%) and saponins (68%). Statistical analysis also disclosed a high correlation (r = 0.85) between the concentration of flavonoids and antimicrobial activity that testifies to their therapeutic significance. Results vindicate scientifically the age-old practice of using plants as drugs in wound healing and establish a basis for their incorporation into contemporary herbal preparations and drug development.

3,815 views
1,151 downloads

Contributors:

 Arnav Roy
,
 Govind Sharma
Research PaperID: IJPHD-00000045

Investigating The Role of Pharmacognosy in The Development of Novel Anticancer Agents

Pratibha Sahu, Deleshwar Kumar

Today Pharmacognosy functions as an essential scientific basis for discovering anticancer medications through research of natural medicating plants alongside additional natural resources. The article evaluates the vital role which pharmacognosy plays when developing compounds that act as cancer treatments. The article describes extraction techniques alongside screening and characterization protocols that help researchers find anticancer compounds among bioactive plant principles. The discovery of pharmacological agents’ taxol and camptothecin and vinca alkaloids stands as one of the primary outcomes alongside their subsequent development into medicinal drugs. The scope includes modern screening procedures linked with molecular docking approaches along with biotechnological growth that enhances both efficiency and pharmaceutical research outcomes in pharmacognosy. The review addresses difficulties alongside existing trends and future guidance about employing natural products for developing oncological drugs.

Phytochemical Screening.Medicinal PlantsPharmacognostic AnalysisWound HealingEthnobotany
3,966 views
1,250 downloads

Contributors:

 Pratibha Sahu
,
 Deleshwar Kumar
Research PaperID: IJPHD-00000046

Pharmacognostic and Phytochemical Investigations of Medicinal Plants: A Systematic Review

arpan tripathi, Rupesh Soni, Shekhar Verma

Medicinal plants have played a central role in India's traditional health care systems, and they have made a valuable contribution to pharmacognosy and phytochemistry. The present systematic review is intended to assess the pharmacognostic and phytochemical attributes of several medicinal plants that are utilized in Indian traditional medicine, such as Ayurveda, Siddha, and Unani systems. The work emphasizes the morphological, microscopic, and physicochemical properties of these plants during the analysis of their bioactive compounds like alkaloids, flavonoids, phenolics, and glycosides. A thorough examination of literature available was done using databases such as PubMed, Scopus, and Google Scholar with emphasis on studies published over the last two decades. The review also touches upon the ethnobotanical importance, therapeutic potential, and standardization issues related to Indian medicinal plants. Research indicates that most of these plants have strong pharmacological activities such as anti-inflammatory, antimicrobial, antioxidant, and anticancer effects. Nonetheless, more extensive research needs to be conducted to determine their clinical utility and safety. This investigation highlights the importance of interdisciplinary approaches that integrate traditional wisdom with contemporary scientific verification to tap the potential of Indian medicinal plants for drugs

Investigating The Role of Pharmacognosy in The Development of Novel Anticancer Agents
3,951 views
1,260 downloads

Contributors:

 arpan tripathi
,
 Rupesh Soni
,
 Shekhar Verma
Research PaperID: IJPHD-00000047

Phytochemical And Pharmacological Evaluation of Traditional Medicinal Plantsfor Antimicrobial Activity

Rishita Pathak, Pratibha Sahu

Ancient medicinal plants have been in use across cultures for the treatment of microbial infections. The recent upsurge in antibiotic resistance has created interest in the discovery of plant-based remedies with antimicrobial activity. In this research, the phytochemical profile and antimicrobial potential of three traditional medicinal plants, Azadirachta indica (Neem), Ocimum sanctum (Tulsi), and Withania somnifera (Ashwagandha), which are well known for their ethnomedicinal uses, were examined. The objective was to evaluate their potential as alternative antimicrobial agents. Phytochemical screening presented the existence of alkaloids, flavonoids, tannins, and saponins in different concentrations in the plant extracts. Antimicrobial activity was determined by the agar well diffusion method, and statistical analysis proved differences in antimicrobial potency among the plant extracts to be significant. Withania somnifera showed the greatest antimicrobial activity, with Ocimum sanctum showing intermediate activity, while Azadirachta indica showed the lowest activity. There was a high positive correlation between the content of alkaloids and antimicrobial activity.

Bioactive compoundsIndian traditional medicinePhytochemistryPharmacognosyMedicinal plants
4,134 views
1,215 downloads

Contributors:

 Rishita Pathak
,
 Pratibha Sahu
Research PaperID: IJPHD-00000048

Synergistic Effects of Herbal Extracts in Combination with Conventional Antibiotics

Arnav Roy, Neelum Chandraker

Conventional antibiotic treatment of bacterial infections is hampered by prevalent antimicrobial resistance. In this research, the synergistic antibacterial activity of different herbal extracts and cefixime against resistant clinical isolates is tested. The preliminary antibiotic susceptibility and antibacterial activity of the herbal extracts were evaluated using disc diffusion and microbroth dilution. Checkerboard experiments, time-kill kinetics, and protein content assays were used to establish synergy. RP-HPLC phytochemical profiling showed high levels of gallic acid (0.24-19.7 μg/mg), quercetin (1.57-18.44 μg/mg), and cinnamic acid (0.02-5.93 μg/mg) in the extracts. 13/16 Gram-negative and 4/6 Gram-positive clinical isolates were resistant to intermediate or total cefixime. Aqueous plant extracts were non-synergistic, whereas ethanolic and methanolic were synergistic. Time-kill kinetics demonstrated that the synergistic interaction reduced bacterial load by 2–8 and was time- and concentration-dependent. The fractional inhibitory concentration index (FICI) combination therapy inhibited growth and protein content (5–62%) in the bacterial isolates from the antibiotic or extract. The research indicates herbal extracts are potential adjuvants to standard antibiotics in resistant microorganisms.

Plant ExtractsFlavonoidsAlkaloidsAntimicrobial ActivityPhytochemical Analysis
4,318 views
1,252 downloads

Contributors:

 Arnav Roy
,
 Neelum Chandraker