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International Journal of Pharmacognosy and Herbal Drug Technology

Published

Evaluation of Anti-Inflammatory Activity of Plant-Based Compounds

Published in IJPHDT, Vol-2, Issue-9, Sep-2025 (Vol. 2, Issue 9, 2025)

Evaluation of Anti-Inflammatory Activity of Plant-Based Compounds - Issue cover

Abstract

The current work used the carrageenan-induced paw edema model in Wistar rats to determine the anti-inflammatory properties of plant-based substances, namely quercetin (Ficus carica) and curcumin (Curcuma longa). Four groups of 24 rats each were created: Quercetin, Curcumin, Standard Drug (Diclofenac), and Negative Control. The volume of paw edema was measured one, two, three, and four hours after induction. Diclofenac showed the greatest suppression of paw swelling at all time periods, while carrageenan was able to successfully produce inflammation in the control group, according to the results. When compared to the control, both curcumin and quercetin considerably decreased inflammation; however, the difference was not statistically significant, with curcumin being slightly more efficient than quercetin. The trustworthiness of these findings was validated by statistical analysis. According to the study's findings, quercetin and curcumin have strong anti-inflammatory properties and could be useful natural supplements or substitutes for traditional synthetic medications.

Authors (4)

Sujit Ramchandra Deshmukh

National institute of technology, Warangal, Telangana, Pin- 46241

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Mayuri Shatrughna Ghadge

Yashvantrao Chavan Institute of Science, Satara, Maharashtra. India, Pin - 415019

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Ajay Vitthal Nalawade

Yashvantrao Chavan Institute of Science, Satara, Maharashtra. India, Pin - 415019

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Ravindra Raghunath Mahajan

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Article Information

Article ID:
IJPHD-00000161
Paper ID:
IJPHD-01-000161

How to Cite

Sujit Ramchandra Deshmukh & Mayuri Shatrughna Ghadge & Ajay Vitthal Nalawade & Ravindra Raghunath Mahajan (2025). Evaluation of Anti-Inflammatory Activity of Plant-Based Compounds. International Journal of Pharmacognosy and Herbal Drug Technology, 2(9), xx-xx. https://ijphdt.scholarjms.com/articles/73

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